ORENCIA (abatacept) is a prescription biologic medicine used to reduce signs and symptoms of moderate to severe Rheumatoid Arthritis in adults 18 years and older. Taking ORENCIA may prevent further damage to your bones and joints, and may help your ability to perform daily activities.

Infusion Experience

The ORENCIA IV infusion is placed in your arm by a healthcare professional. Each infusion takes about 30 minutes, though actual time in the clinic will be longer.*

It is approved to be used by adults with moderate to severe RA, active PsA, or children 6 years or older with pJIA.

*The initial infusion schedule includes treatment at Days 1, 15, 29, and every 4 weeks thereafter.

Possible Side Effects

Talk to your rheumatologist about any side effect that may be bothering you. Your rheumatologist can work with you to manage side effects throughout your treatment.

The most common side effects of ORENCIA include:

  • Headache
  • Upper respiratory tract infection
  • Sore throat
  • Nausea

In children and adolescents, other side effects may include:

  • Diarrhea
  • Cough
  • Fever
  • Abdominal pain

These are not all of the possible side effects of ORENCIA. If you have any questions or want more information about side effects, ask your rheumatologist or healthcare provider.